The CYBER team shares its research through publications, talks and posters at conferences, outreach activities and engagement with industry and the public. Find out more below about the work we have published, where we have presented it, and the funding that supports it.
Impact
Publications
Characterization of recombinase-based genetic parts and circuits using nanopore sequencing
Greco F.V., Cameron S.K., Joshi S.H.-N., Brophy J.A.N., Grierson C.S. & Gorochowski T.E.
Nature Communications 17, 2026
Canonical transcription termination mechanisms explain a minority of operons in cyanobacteria
Cascino J.A., Dierksheide K.J., Vishwakarma R.K., Yuzenkova Y., Babitzke P., Murakami K.S. & Li G.-W.
mSystems 11, e01581-25, 2026
Knowledge preservation in the era of big science and AI: strategies for sustainable scientific research
Rainford P.F., Occhipinti A., Wang B., Stepney S., Angione C., Verma S., Marucci L., Sharma K., Harris S., Füchslin R.M., Klipp E., Grierson C.S., Weyland M.S., Mogre A., Fellermann H., Doan L.M.T, Gherman I., Pyne A., Rudge T.J., Berrelleza V.M.V. & Gorochowski T.E.
Nature Communications 17, 4069, 2026
From FAIR to CURE: guidelines for computational models of biological systems
Sauro H.M., ..., Gorochowski T.E., ... & Moraru I.
npj Systems Biology and Applications 12, 77, 2026
Signatures of Electron–Hole Hopping in Myoglobin Peroxidase Activity Revealed by Deep Mutational Learning
Küng C., Dalkıran A., Vanella R., Oyarzún D.A. & Nash M.A.
ACS Catalysis 16, 6600–6613, 2026
Data-driven inference of digital twins for high-throughput phenotyping of motile and light-responsive microorganisms
Giusti A., Salzano D., di Bernardo M. & Gorochowski T.E.
Journal of the Royal Society Interface 23, 20250780, 2026
SHARK: a specialized host for assembling R6K plasmids
Joshi S.H.-N., Jenkins C., Ulaeto D. & Gorochowski T.E.
ACS Synthetic Biology 15, 867–875, 2026
Emerging trends in genome integration tools for precision engineering of diverse bacterial species
Rohmat R.K., Irvine T., Joshi S.H.-N., Bailey A., Jenkins C., Ulaeto D., Buscaill P. & Gorochowski T.E.
Synthetic Biology 10, ysaf019, 2025
Optimization of regulatory DNA with active learning
Shena Y., Kudlab G. & Oyarzún D.A.
Computational and Structural Biotechnology Journal 27, 4384–4392, 2025
The Japan-UK Synthetic Biology Conference, Spring 2025: strengthening global links to engineer biology
Gorochowski T.E., Brockhurst M.A., Ceroni F., Iwasaki Y.W. & Yachie N.
ACS Synthetic Biology 14, 1873-1878, 2025
Cas9-based enrichment for targeted long-read metabarcoding
Nikolaeva-Reynolds L., Cammies C., Crichton R. & Gorochowski T.E.
Royal Society Open Science 12, 242110, 2025
Engineering Biology Applications for Environmental Solutions: Potential and Challenges
Lea-Smith D.J., Hassard F., Coulon F., Partridge N., Horsfall L., Parker K.D.J., Smith R.D.J., McCarthy R.R., McKew B., Gutierrez T., Kumar V., Dotro G., Yang Z., EBIC partners & Krasnogor N.
Nature Communications 16, 3538, 2025
Talks
Optimising genetically engineered microorganisms using ‘Ecological Wind Tunnels’, Fundamental to Applied Biosciences Conference, Bristol, UK, 2025 (Joseph Pennycook)
Unravelling the role of ecology when engineering biology, UKRI Engineering Biology Mission Hubs and Mission Awards Science Showcase, Manchester, UK, 2025 (Joseph Pennycook)
Does ecological stress alter the function of genetically engineered cyanobacteria?, Molecular Microbial Ecology Conference, Birmingham, UK, 2025 (Joseph Pennycook)
Cyanobacteria Engineering for Restoring Environments (CYBER), AlgaeCytes, Kent, UK, 2025 (Shylaja Mohandass)
Genome-wide identification of putative neutral sites for engineering biology, UKRI Engineering Biology Mission Hubs and Mission Awards Science Showcase, Manchester, UK, 2025 (Yasir Akbar)
Sequence-to-expression optimization with machine learning, UKRI Engineering Biology Mission Hubs and Mission Awards Science Showcase, Manchester, UK, 2025 (Yasir Akbar)
Industrial Biotechnology Innovation Catalyst (IBIC) Conference, Manchester, UK, 2025 (Thierry Le Goff, NML)
ASEAN-UK Regional Training & Workshop, London, UK, 2025 (Julian Braybrook, NML)
Deep mutational learning for effective enzyme engineering, Synthetic Biology UK, London, UK, 2025 (Alperen Dalkıran)
Biological design with machine learning and limited data, AI Hub in Generative Models, UCL, London, UK, 2025 (Diego Oyarzún)
Biological design with machine learning and limited data, University of Cambridge, Cambridge, UK, 2025 (Diego Oyarzún)
Sequence-to-expression prediction using mRNA secondary structure information (invited keynote), PEGS Europe, Lisbon, Portugal, 2025 (Diego Oyarzún)
Sequencing-based methods for accelerated cellular programming, Japan-UK Synthetic Biology Conference, Osaka, Japan, 2025 (Thomas Gorochowski)
Programming biological systems across scales using synthetic biology (invited keynote), 29th IEEE International Symposium on Asynchronous Circuits and Systems, Portland, USA, 2025 (Thomas Gorochowski)
What does the future of synthetic biology look like? (invited keynote), Microbial Engineering Symposium, Cambridge, UK, 2025 (Thomas Gorochowski)
Data-centric approaches to biological design and engineering (invited keynote), Multimodal AI Conference, London, UK, 2025 (Thomas Gorochowski)
Interconnections and Cross-Regulation of Gene Expression Processes, Göttingen, Germany, 2025 (Yulia Yuzenkova)
Programming biological systems across scales using synthetic biology, CBS Research Seminar, Montpellier, France, 2025 (Thomas Gorochowski)
Deciphering Picosynechococcus genome to identify neutral sites for synthetic barcode integration, EBIC ECR Conference, Edinburgh, UK, 2025 (Yasir Akbar)
Annual International RNA Polymerase Workshop, Birmingham, UK, 2025 (Moubani Chakraborty)
Posters
UKRI Engineering Biology Mission Hubs and Mission Awards Science Showcase, Manchester, UK, 2025 (Moubani Chakraborty)
From parts to program – genetic toolkit for reprogramming cyanobacteria, UKRI Engineering Biology Mission Hubs and Mission Awards Science Showcase, Manchester, UK, 2025 (Shylaja Mohandass)
Genome-wide identification of putative neutral sites for engineering biology, Synthetic Biology UK, London, UK, 2025 (Yasir Akbar)
Outreach and Wider Engagement
The science of microplastics: what exactly are microplastics and why we should care, The Science Tapes Podcast, Bristol, UK, 2025 (Joseph Pennycook)
Industrial visit, AlgaeCytes, Kent, UK, 2025 (Shylaja Mohandass)
Funding
International Exchange, Royal Society, IES\R1\251443, 2025–2027 (£12,000; PI: Thomas Gorochowski, Co-I: Samuel Schaffter)
Bio-Security Prevent and Respond Programme, DSIT, 2025–2026
Travel Scholarship, AlgaeCytes, 2025 (£200; PI: Shylaja Mohandass)
Engineering Biology Seed Corn, UKRI, BB/Y007638/1, 2025–2026 (£70,088; PI: Thomas Gorochowski, Co-Is: Christopher Clements, Diego Oyarzún, Natalio Krasnogor, Yulia Yuzenkova)
Engineering Biology Mission Award, UKRI, BB/Y007638/1, 2024–2026 (£1.9M; PI: Thomas Gorochowski, Co-Is: Christopher Clements, Diego Oyarzún, Natalio Krasnogor, Yulia Yuzenkova)
